![]() Generative AI co-pilots for sales representatives, for example, were mapped to the commercial domain.įor generative AI use cases (such as synthesizing scientific literature) that affect multiple life-science domains, we based our allocation of the economic impact on the relative size of the relevant domains, as well as expert opinion. ![]() Each of them was then mapped to a specific life-science domain-an exercise based on the typical activities performed within it. We based the potential economic impact of gen AI in different domains of the life sciences on the McKinsey Global Institute’s analysis of its impact in 63 individual use cases. These leaders used their extensive work helping clients deploy gen AI over the past year to identify the use cases most likely to spark meaningful near-term productivity gains and economic value. Those numbers in hand, we tapped the experience and knowledge of McKinsey’s leaders in each domain. So we dug deeper into MGI’s data and modeling of 63 generative AI use cases in the life sciences and calculated the potential economic impact for five industry domains: research and early discovery, clinical development, operations, commercial, and medical affairs. ![]() With compelling new gen AI use cases emerging, we were eager to understand, in a more granular way, the most promising areas of potential value (see sidebar “A guide to our methodology”). AlphaFold2, ESMFold, and MoLeR, for example, all use deep learning to help predict the structures of nearly all known proteins, transforming our understanding of their underlying diseases. Even before last year’s explosion of interest, researchers were applying complex AI models to unlock the mechanisms of disease. Pharmaceutical companies, of course, have long been in the vanguard of artificial intelligence. This report is a collaborative effort by Chaitanya Adabala Viswa, Joachim Bleys, Eoin Leydon, Bhavik Shah, and Delphine Zurkiya, representing views from McKinsey’s Life Sciences Practice.
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![]() We're also fans of this chair's aesthetic, which seems to simultaneously channel both high-end patio furniture and classic camping chairs to create a luxurious yet athletic vibe. Combined with solid cast joints, it's basically indestructible. The mesh FlexGrid fabric is totally breathable and incredibly strong, with the ability to support up to 500 pounds of weight without stretching out. But its impressive durability, superior comfort, and sleek look are worth the higher price tag, if you can swing it. On the opposite end of the price spectrum is the Yeti Hondo Base Camp Chair, which is a serious splurge. Who it's not for: People looking for a lightweight option. Who it's for: People who can afford to splurge on a stay-put chair. Materials: Steel and polyester | Dimensions: 24 x 18.1 x 9.1 inches | Weight: 8.3 pounds | Weight Capacity: 325 pounds But for car camping, tailgating, or any other activity that doesn't require a long trek with your chair, this is by far the best budget choice. The only downside is that this chair weighs 8.3 pounds, which can be a deterrent for adventurers who like to hike to their campsite. The other armrest includes a cup holder for your open beverage, while a handy side pocket is attached to hold snacks, reading materials, or keys. ![]() One armrest is equipped with a built-in insulated pouch that keeps up to four cans chilled, so you'll never be without a refreshing drink. ![]() If you're not already sold, then maybe the features will convince you. Its affordable price tag simply cannot be beat for what you're getting, which is an exceedingly comfortable polyester-cushioned seat paired with a sturdy steel frame that can support over 300 pounds of weight. When it comes to the best budget lawn chair, the Coleman Quad Camp Chair is the undoubtable winner. Who it's not for: People who want a more aesthetically-pleasing lawn chair. Who it's for: People looking for a comfortable camping chair on a budget. View On Amazon $32 View On Walmart $62 View On Material: Aluminum and textile | Dimensions: 32 x 24 x 21.5 inches | Weight: 4.2 pounds | Weight Capacity: 225 pounds Those looking for additional room in the seat can opt for the Magnum version, while picnickers might prefer the equally tall, yet more compact, Picnic style chair. While we're partial to this Classic version, which sits at an ideal 15.5 inches above the ground, this chair is also available in both a low-back and high-back beach chair option, which are much shorter. ![]() The kit is also useful to restore well-worn chairs, but buyers needn't worry about excessive wear any time soon-though the webbing will slightly stretch, the seat won't sag and the fabric is fade-resistant. Those concerned with aesthetics will also be pleased to know that the Lawn Chair USA Webbing Chair is available in a ton of colors and can be re-webbed with a replacement lawn chair webbing kit if you want an update. But with a vintage-style look, it's not too sporty to serve as full-time backyard seating. The rust-free aluminum frame and UV-resistant webbing are incredibly lightweight and easy to fold up, so the chair is portable for camping, tailgating, and hanging in the park. The Lawn Chair USA Webbing Chair is our top pick because it's a universal lawn chair that works for a variety of uses. Who it's not for: People who are interested in extra features. Who it's for: People seeking a classic, no-frills lawn chair that comes in a variety of colors. There’s no way to see where these pitfalls are ahead of time, so by the time you fall into one it’s already too late. ![]() In Sonic Rush, more than ever will you have to worry about how many lives you’ve got left, because there are deadly pitfalls all over the place. One thing that certainly sets Sonic Rush apart from previous Sonic titles is the level of difficulty. These stages are played by controlling Sonic with the stylus – and these are the stages where you can collect the seven Chaos Emeralds, and potentially unlocking the ultimate power of Sonic. There’s also the hidden special stages where Sonic is rushing down a pipe and he is seen from behind, just like in Sonic the Hedgehog 2. Sonic Rush also lets you swing in ropes and bash through walls. Tricks can also be used to build up your tension gauge. You can perform tricks in the air or while grinding on rails, and the more tricks you pull off the better your score will be. There are other minor new features included too, such as the ability to do tricks. This is a prime example of a new feature that really works well and could easily be implemented into future Sonic titles to add a new layer of depth and excitement. So to maximize your time records, you’d need to balance your game between finding the fastest possible path through each of the levels, fighting enemies, and bursting away with Super Boost. This tension can be used to perform a special move called Super Boost (or Fire Boost for Blaze) that gives you an insane burst of speed. The bars fill up very easily, so most of the time you don’t really have to worry about it. This is shown as a gauge that builds up when you hit enemies, for example. This is a special feature to measure your character’s tension. Not only are the levels filled with trampolines and devices that allow you to perform all-new kind of stunts and jumps, but you’ve also been granted a so-called ‘tension gauge’. But at the same it works well with the story and seeing the levels are so large, they really offer many paths and you’ll keep discovering new secrets and alternative routes even on your tenth time through. You might think that this is a cheap way to add length and replay value to a mere eight zones, and I partly agree. Depending on who you play as, you’ll be able to reach different areas and paths in each of the zones thanks to their different moves – Sonic is fast, but Blaze can spin up into a flaming tornado and briefly float in the air thanks to this. Sonic and Blaze will visit the same areas, but in a different order. During the course of the game you’ll be visiting many entirely new locations such as the Night Carnival (that reminds us about the Casino Night Zone in Sonic the Hedgehog 2), and the lush Leaf Storm Zone. The acts in turn are huge and have many secret and alternative paths – it’s quite breathtaking to be speeding around in a level that’s so open in every direction. In total there are eight zones to play in, and each zone except the last one consists of two acts and a boss act. ![]() In practice this means that there are two parallel stories going on at the same time, and they intertwine with one another. ![]() They both start at different locations in the world as they both are looking for Eggman’s whereabouts and the emeralds known as Sol Emeralds. ![]() Before you start playing the single-player story mode, you’ll be prompted to choose whether you want to play as Sonic or Blaze. ContentĪs well as having the novel experience of playing Sonic on a portable device, you’ll also be introduced to the new mysterious character to the Sonic universe named Blaze the Cat. Sonic and the other characters are rendered in 3D this time around, but the game still plays like a normal 2D side-scroller, with the exception of the boss fights which are all in full 3D. As such, the game is a pretty standard side-scrolling platform game with a few quirks mixed into it. It builds heavily on the basic and well-known Sonic formula a lightning fast platform game where you run around on a level, starting at point A and trying to reach point B. Sonic Rush is the first Sonic game to appear on the Nintendo DS hand-held console.
The /new/ board was the direct predecessor to /pol/. This was comparing /new/ to Stormfront, which is the oldest and largest Holocaust-denialist white supremacist site. According to 4chan's creator and ex-administrator Christopher Poole, this was because it had "devolved into / stormfront/". It was deleted a year later on 17 January 2011. Īnother news board, /new/, was later added on 25 January 2010. n/'s topic was changed to transportation on 19 February 2008, without moving the news topic to another board, effectively removing it. It replaced /n/'s previous topic of animals and nature, which was moved to the /an/ board. The first of these was /n/, which was added on 8 April 2006. ![]() Prior to the creation of /pol/, there were two boards intended for discussing news that had been added and removed from the site. However, 4chan's /pol/ board has become increasingly "synonymous with 4chan as a whole", according to New Media & Society. These include Kohlchan, 8chan (later 8kun), 16chan, Shitchan, and Endchan, with some less popular "/pol/" themed boards accessible through the Tor network on sites such as 9chan and Neinchan. While 4chan's /pol/ board is the most popular board under the "/pol/" name, versions on other websites have existed. According to Mic, "On a place like /pol/, there's no clear delineation between sincerity, irony and cynicism." First Monday commented that "The creation of character-based archetypes is common on /pol/ and makes this online space semi-performative and semi-authentic." Many have questioned the sincerity of users on /pol/ as possible trolls. Much of the content on /pol/ relies heavily on Internet memes to further spread ideas. Threads have a limited lifespan, effectively prioritizing newer content. However, these unique IDs will only tend to remain attached to a user per a single thread, as they are not persistent between multiple threads. Įach post also has a unique ID attached, which is likewise associated with the user's IP address. ![]() However, these are not common per amount of posts-the "Nazi" meme flag was the most commonly used meme flag in a 2020 analysis, while posts with an American geographic location were about 57 times more common (and appeared the most of any flag). ![]() Alternatively, users may select a "meme flag" (also referred to as a "troll flag"), corresponding to various political identifiers. A national flag corresponding to the user's geographic location based on their IP address may be displayed. Outside of traditional news sources, users also commonly rely on alternative media such as YouTube commentary as a source of news. A 2020 report categorized about 36% of news sources frequently posted to the board by American users as " junk news", a category that includes sources considered to be propaganda, sensationalist, or conspiracy theory content. Overview Screenshot of the front (catalog) page of /pol/ in December 2019, with each discussion thread indicated by an imageĬommon /pol/ content involves discussion of history, far-right ideologies, hatred of black people, hatred and sexual exploitation of women and girls and current news. It has been described as one of the " of 4chan mobilization", a title also ascribed to /b/. pol/ has been linked to various acts of real-world extremist violence. It has acted as a platform for far-right extremism the board is notable for its widespread racist, white supremacist, antisemitic, anti-Muslim, misogynist, and anti-LGBT content. It has had a substantial impact on Internet culture. ![]() As of 2022, it is the most active board on the site. pol/, short for " Politically Incorrect", is an anonymous political discussion imageboard on 4chan. ![]() ![]() Accurate translation for transcripts and voice overs. Take your content global and translate to and from 70+ languages in seconds. 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